The Doctor’s Heart Cure By Al Sears, M.D ( Telomerase and TA-65)
Telomerase and TA 65
This article examines problems scientists solved (Elizabeth Blackburn, Carol Greider, and Jack Szostak) which eventually led to them winning the telomerase Nobel Prize in Physiology or Medicine 2009. Telomerase: the photocopier of cells
A big problem in biology is how a chromosome is able to be copied in a complete way during cell divisions and how chromosomes were protected against degradation. The three scientists showed that the solution to the problem is the end of the chromosomes, telomeres, and an enzyme that quickly forms the telomeres. Telomerase in action DNA molecules carry genes and are packed into chromosomes and at the end of these chromosomes are telomeres. One unique DNA sequence which is found in telomeres is what protects the chromosomes from degradation. Also, telomerase was found to be an enzyme that produces telomere DNA.
What this shows is that the ends of chromosomes are protected by telomeres that are produced by telomerase. With this knowledge scientists can conclude that as telomeres shorten, a cell ages. So, if telomerase activity is high, the telomere can maintain length, and delay cellular senescence. This can explains how cancer cells have eternal life and also how inherited diseases, which have defective telomerase, result in damaged cells.
Discoveries such as this have had a huge affect on the scientific community. Scientists have been attempting to discover how we age since the beginning of time and they have speculated that the shortening of telomeres is the reason for not only individual cells but for a whole organism. While telomeres are one factor, it turns out the aging process is far more complicated than previously thought.
Cancer and telomerase
Normal cells do not divide frequently, so they are rarely at a risk of shortening and have low telomerase activity. What the telomerase Nobel Prize explains though is that cancer cells have high levels of telomerase activity. What they hypothesize is cancer could be treated by destroying the telomerase.
Telomerase has also been tied to other diseases
It is also been found that telomerase defects are a leading cause of inherited diseases such as some forms of congenital aplastic amenia. This disease is insufficient where cell divisions in the stem cells of the bone marrow lead to severe anemia. It is being hypothesized that we could fix these harmful diseases by fixing the telomerase defect.
The discoveries by Blackburn, Greider, and Szostak were able to win them the telomerase Nobel Prize in Physiology or Medicine for 2009. Their telomerase discoveries have greatly impacted the scientific community and will hopefully help solve the problems of aging, cancer, inherited diseases, and many many more!
Telomerase is a key enzyme in the human and it has been proven to lengthen telomeres. To learn more visit thewww.thevitaminspa.com web site.
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